The AI industry kicked off 2025 with impressive energy.
In 2024, there were 49 startups that secured funding rounds exceeding $100 million, according to TechCrunch’s tally. Notably, three companies managed to pull in more than one “mega-round,” and seven companies netted rounds of $1 billion or larger.
The momentum didn’t wane in 2025. Even though fewer companies raised rounds higher than $1 billion—four in total, with Anthropic raising two exceeding that mark—more companies participated in multiple funding rounds compared to 2024, totaling eight.
What will 2026 bring? Sam Altman’s brain-computer interface startup Merge Labs has already raised a $250 million seed round, led by OpenAI, and Elon Musk’s xAI has announced plans for a $20 billion Series E round in early 2026. So far, indications suggest another robust year ahead. However, as it’s still early in the year, we’ll keep a close eye on whether this momentum continues.
Here’s a list of U.S. AI companies that raised $100 million in the past year:
December:
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Mythic (Austin, Texas): This company, focused on power-efficient computing for AI, raised $125 million in a venture round announced on December 17, led by DCVC and joined by investors including SoftBank, NEA, and Linse Capital.
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Chai Discovery: Announced a $130 million Series B round on December 15, valuing the biotech and drug discovery AI firm at $1.2 billion. This round was co-led by Oak HC/FT and General Catalyst.
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Fal: The generative media platform raised a $140 million Series D round on December 9, led by Sequoia, valuing the company at over $4.5 billion.
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Unconventional AI: This startup, rethinking computer foundations in the AI era, secured a remarkable $475 million seed round on December 8, co-led by Lightspeed Venture Partners and Andreessen Horowitz, valuing it nearly at $4.5 billion.
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7AI (Boston): Specializing in cybersecurity AI agents, raised a $130 million Series A round announced on December 4, led by Index Ventures with other participants including Greylock, Spark Capital, and CRV.
November:
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Genspark: An all-in-one AI workspace platform that raised $275 million in Series B funding on November 20, valuing it at $1.25 billion. The round included Emergence Capital Partners, SBI Investment, and LG Technology Ventures.
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Luma AI: This company, specializing in photo and video creation models, secured $900 million in a Series C round, valuing it at $4 billion, led by Humain with participation from Andreessen Horowitz, AMD Ventures, and Amplify Partners.
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Anysphere: Known for its viral vibe-coding platform Cursor, raised a staggering $2.3 billion on November 13, bringing the company’s total valuation to $29.3 billion in its second funding round of the year.
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Parallel: This firm, focused on AI agent web infrastructure, raised $100 million in Series A funding announced on November 12, co-led by Index Ventures and Kleiner Perkins.
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Hippocratic AI: The healthcare AI agent startup raised $126 million in its Series C round on November 3, valued at $3.5 billion and led by Avenir Growth.
October:
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Fireworks AI: This platform, enabling users to build AI applications with open-source models, raised $250 million in Series C funding announced on October 28, valuing it at $4 billion.
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Uniphore: Valued at $2.5 billion after a $260 million Series F round announced on October 22, with participation from Snowflake Ventures, Nvidia, Databricks Ventures, and AMD.
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Sesame: A voice AI company that raised a $250 million Series B round, co-led by Sequoia and Spark Capital, announced on October 21.
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OpenEvidence (Cambridge, Massachusetts): An AI chatbot developer for medical applications raised a $200 million Series C round on October 20, valuing the company at $6 billion.
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Lila Sciences: Announced a $350 million Series A round on October 14 for its science superintelligence platform, co-led by Braidwell and Collective Global.
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Reflection AI: Its second mega-round happened on October 9, with a $2 billion Series B round valuing the company at $8 billion, led by Nvidia.
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EvenUp: This firm building AI for personal injury law announced a $150 million Series E round, valuing it at over $2 billion, on October 7, led by Bessemer with participation from Lightspeed, Bain Capital, and SignalFire.
September:
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Periodic Labs: They announced a $300 million seed round on September 30, co-led by Felicis and Andreessen Horowitz with additional backing from Nvidia, Lightspeed, and Khosla Ventures.
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Cerebras Systems: This AI infrastructure company raised a $1.1 billion Series G round on September 30, co-led by Fidelity and Atreides Management, valuing it at $8.1 billion.
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Modular: Raised $250 million on September 24, led by US Innovative Technology Fund and joined by GV, Greylock, and General Catalyst.
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Distyl AI: With its AI enterprise software, raised a $175 million Series B round on September 23, valuing the startup at $1.8 billion with investors like Khosla Ventures and Lightspeed.
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Upscale AI: This startup, focused on AI infrastructure, raised $100 million in seed funding on September 17, co-led by Maverick Silicon and Mayfield, also involving StepStone Group and Stanford University.
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Groq: Announced a $750 million Series D-3 round on September 17, valuing the company at nearly $6.9 billion.
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Invisible Technologies: Valued at $2 billion after a $100 million fundraise, announced on September 16, with funding led by Vanara Capital and participation from Greycroft, Tallwoods Capital, and Freestyle Capital.
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Cognition AI: Creator of vibe-coding agent Devin, raised a $400 million Series C round announced on September 8, led by Founders Fund, valuing it at $10.2 billion.
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Baseten: An AI infrastructure startup that raised a $150 million Series D round on September 5, valued at $2.1 billion, led by Bond.
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Sierra: Bret Taylor’s customer service AI platform raised $350 million in funding announced on September 4, valued at over $10 billion, led by Greenoaks Capital.
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You.com: This personalized AI search engine announced a $100 million Series C round on September 3, led by Cox Enterprises, valuing it at $1.5 billion.
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Anthropic: The AI research lab raised a massive $13 billion Series F round on September 2, valuing it at $183 billion, led by Iconiq, Fidelity, and Lightspeed.
August:
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EliseAI: This healthcare and housing automation platform raised $250 million in a Series E round on August 20, valuing it at $2.2 billion, led by Andreessen Horowitz.
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Decart: An AI research lab that raised $100 million at a $3.1 billion valuation, announced on August 7 with participation from Sequoia Capital, Benchmark, and Zeev Ventures.
July:
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Fal: This generative media platform raised $125 million in Series C funding announced on July 31, valuing it at $1.5 billion, led by Meritech Capital Partners.
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Ambience Healthcare: A five-year-old company developing an AI healthcare operating system raised $243 million in its Series C round, led by Oak HC/FT and Andreessen Horowitz.
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Reka AI: Announced a $110 million Series B round on July 22, with participation from Snowflake and Nvidia, valuing the company at $1 billion.
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Thinking Machines Lab: This AI research lab confirmed a $2 billion seed round on July 15, led by Andreessen Horowitz with support from Nvidia, Accel, and AMD, valuing it at $12 billion.
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OpenEvidence: Raised $210 million at a $3.5 billion valuation on July 15, led by Kleiner Perkins and GV.
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Harmonic: This company, building a mathematical reasoning engine, raised a $100 million Series B round, announced on July 10, valuing it at $875 million.
June:
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Abridge: This healthcare AI startup raised a $300 million Series E round, valuing it at $5.3 billion, led by Andreessen Horowitz and Khosla Ventures.
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Harvey: The legal tech AI company announced another $300 million Series E round on June 23, co-led by Kleiner Perkins and Coatue, raising its valuation to $5 billion.
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Tennr: This healthcare AI startup raised $101 million in Series C funding, led by IVP with participation from Lightspeed Venture Partners, GV, and Andreessen Horowitz, bringing its value to $605 million.
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Glean: The enterprise search startup secured a $150 million Series F round on June 10, valuing it at $7.25 billion, led by Wellington Management with participation from Sequoia, Lightspeed Venture Partners, and Kleiner Perkins.
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Anysphere: Raised $900 million in a Series C round, valuing it at nearly $10 billion, led by Thrive Capital with participation from Andreessen Horowitz, Accel, and DST Global.
May:
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Snorkel AI: The AI data labeling startup raised a $100 million Series D round on May 29, valuing it at $1.3 billion, led by Addition with participation from Prosperity7 Ventures and others.
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LMArena: A community-driven AI benchmarking tool that raised a $100 million seed round, valuing it at $600 million, announced on May 21, co-led by Andreessen Horowitz and UC Investments.
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TensorWave: This Las Vegas-based AI infrastructure company announced a $100 million Series A round on May 14, co-led by Magnetar Capital and AMD Ventures.
April:
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SandboxAQ: Closed a $450 million Series E round on April 4, valuing the AI model company at $5.7 billion, with notable investors like Nvidia and Google.
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Runway: Raised $308 million in a Series D round announced on April 3, valuing it at $3 billion, led by General Atlantic.
March:
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OpenAI: This AI giant raised an unprecedented $40 billion funding round on March 31, valuing the startup at $300 billion, led by SoftBank and backed by Thrive Capital, Microsoft, and others.
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Nexthop AI: Announced a $110 million Series A round on March 25, led by Lightspeed Venture Partners.
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Insilico Medicine: The generative AI drug discovery platform announced a $110 million raise on March 13, valued at $1 billion, co-led by Value Partners and Pudong Chuangtou.
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Celestial AI: Raised a $250 million Series C round on March 11, bringing its valuation to $2.5 billion, led by Fidelity.
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Lila Sciences: Raised a $200 million seed round on March 7 to develop a science superintelligence platform.
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Reflection.Ai: The Brooklyn-based superintelligent systems company secured a $130 million Series A round on March 7, valuing it at $580 million.
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Turing: Closed a Series E round on March 7, valuing the coding startup at $2.2 billion, led by Khazanah Nasional.
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Shield AI: Raised $240 million in a Series F round on March 6, valuing it at $5.3 billion.
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Anthropic: The AI research and large language model company raised $3.5 billion in a Series E round on March 3, valuing it at $61.5 billion.
February:
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Together AI: Created infrastructure for open-source generative AI, raised $305 million in a Series B round valued at $3.3 billion.
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Lambda: Announced a $480 million Series D round on February 19, valued at nearly $2.5 billion.
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Abridge: This platform that transcribes clinician conversations raised $250 million in a Series D round announced on February 17, valued at $2.75 billion.
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Eudia: The AI legal tech company raised $105 million in a Series A round led by General Catalyst on February 13.
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EnCharge AI: A hardware startup that raised $100 million in a Series B round on February 13.
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Harvey: Raised a $300 million Series D round, valuing the AI legal tech firm at $3 billion.
January:
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ElevenLabs: This synthetic voice startup raised a $180 million Series C round, valuing it at over $3 billion, announced on January 30.
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Hippocratic AI: Developing language models for healthcare, raised $141 million in Series B funding on January 9, valued at over $1.6 billion.
This piece was last updated on April 23, June 18, August 27, November 26, and January 19, 2026, to reflect additional deals.
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This article has been updated to clarify that Abridge was founded in Pittsburgh, though it is not currently based there.
